Laminins - cell differentiation, phenotype stability, pancreatic island expansion

Most cell types in the body are located on or directly attached to thin connective tissue structures (basement membranes) that contain specific laminin proteins, which come in over 16 different forms and are tissue-specific. The laminins are important for cell differentiation binding and for the tissue-specific stability of cells. We are the only research group that has produced these highly complex proteins and studied them. We have shown that laminins have several